With thirty years of experience performing as soloists as well as in various saxophone quartets, music ensembles and chamber music groups, Gianpaolo Antongirolami, Roberto Micarelli, Luca Mora and Gabriele Giampaoletti decided to form the Alea Saxophone Quartet in 2006.
Before reconfiguring itself as a contemporary music ensemble, the Alea Saxophone Quartet previously concentrated on early 20th Century French music, as well as on the crossover between jazz and classical music. The reason for this newer direction was to broaden the scope of their sound and to expand their repertoire.
The Alea Saxophone Quartet engaged with the works of some of the most important European and American composers of the second half of the 20th and the early 21st centuries, including Sciarrino, Donatoni, Xenakis, Andriessen, Cage, Riley, Nyman, Reich, Glass, Lang, Fitkin and Torke. They performed works by the above composers at major contemporary music festivals and most notably, Salvatore Sciarrino's Pagine at the 4th Centenary Celebrations of the birth of Carlo Gesualdo da Venosa. Several of the group's performances were recorded and broadcast by RAI-Radio 3, including the Rassegna di Nuova Musica in Macerata.

The renowned Arvo Pärt project was a significant milestone in the group's artistic odyssey. In 2015, on the occasion of Arvo Pärt's 80th birthday, the Alea Saxophone Quartet performed the complete saxophone quartet works by the Estonian composer at a string of concerts throughout Italy. At the 70th edition of the Sagra Musicale Umbra, six out of eight of these compositions were world premieres.
Aside from performing with the Alea Saxophone Quartet, individual members have regularly appeared at other international events in Italy, Austria, Germany, France, Croatia, Switzerland, England, Spain, Romania, Israel and the USA. Musical collaborations include luminaries such as Terry Riley, Butch Morris, Mike Svoboda, Garth Knox, Arno Bornkamp, Horacio Vaggione, Giancarlo Schiaffini, Stefano Scodanibbio, Otis Murphy, Roberto Fabbriciani, Alvise Vidolin, Michele Lo Muto, Matteo Cesari, Daniele Roccato and Marcus Weiss.
A number of recording sessions by the quartet have also been broadcast on national radio and television. As an ensemble as well as solo musicians, members have performed with the Orchestra Sinfonica della RAI, the Orchestra Filarmonica del Teatro La Fenice in Venice, the Orchestra i Pomeriggi Musicali di Milano, the Orchestra del Teatro Lirico di Cagliari, the Orchestra Haydn di Trento e Bolzano, the Orchestra Filarmonica Marchigiana, the Orchestra Sinfonica di Bari, the Orchestra Internazionale d'Italia, the Bordeaux-Aquitaine Orchestra and the Oradea State Philharmonic Orchestra in Romania.
Members of the Alea Saxophone Quartet are also involved in didactical activities, teaching saxophone at various music conservatories in Italy. Regular master classes are held at institutions throughout Europe, including Keele University and Edinburgh University (UK), Hochschule für Musik Freiburg (Germany) and Mozarteum University Salzburg (Austria).